The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2003
Filed:
Jan. 05, 2001
Applicant:
Inventors:
Nader Fotouhi, Chatham, NJ (US);
Paul Gillespie, Westfield, NJ (US);
Robert William Guthrie, Saddle Brook, NJ (US);
Sherrie Lynn Pietranico-Cole, Montclair, NJ (US);
Weiya Yun, Warren, NJ (US);
Assignee:
Hoffman-La Roche Inc., Nutley, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C / ; C07D / ; C07D / ; A61K 3/1167 ; A61P 1/706 ;
U.S. Cl.
CPC ...
C07C / ; C07D / ; C07D / ; A61K 3/1167 ; A61P 1/706 ;
Abstract
Aromatic dehydroamino acids are disclosed that are active as LFA-1 arnagonists This activity enables these compounds to prevent inflammation which is a consequence of T cell activation and accordingly reduce or eliminate inflammatory skin disease psoriasis.