The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2003
Filed:
Oct. 01, 1996
Applicant:
Inventors:
Shao-Chieh Juan, Moorpark, CA (US);
Frederick A. Fletcher, Camarillo, CA (US);
Scott D. Patterson, Newbury Park, CA (US);
Assignee:
Amgen Inc., Thousand Oaks, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07H 2/104 ;
U.S. Cl.
CPC ...
C07H 2/104 ;
Abstract
A new member of a family of ICE-like cysteine proteases has been identified. The protease family is termed LICE (Like ICE) and the family member described herein is LICE3. LICE3 polypeptides, nucleic acids encoding LICE3 and vectors and host cells for the expression LICE3 are disclosed. Also disclosed are methods for identifying LICE3 agonists and antagonists, and methods for treatment of disorders characterized by altered apoptosis.