The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2003
Filed:
Aug. 19, 1998
Applicant:
Inventors:
Dalton King, Hamden, CT (US);
Raymond A. Firestone, Ridgefield, CT (US);
Pamela Trail, Yardley, PA (US);
Assignee:
Bristol Myers Squibb Company, Princeton, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 1/702 ; C07H 1/700 ; C07H 1/504 ; C07H 1/512 ;
U.S. Cl.
CPC ...
C07H 1/702 ; C07H 1/700 ; C07H 1/504 ; C07H 1/512 ;
Abstract
Branched hydrazone linkers for linking a targeting ligand such as an antibody to a therapeutically active drug. The point of branching is at a polyvalent atom and the number of drugs increases by a factor of two for each generation of branching. A preferred drug is doxorubicin.