The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2003
Filed:
Jul. 06, 2000
Applicant:
Inventor:
Helen Logothetou-Rella, Athens, GR;
Assignee:
Norsk Hydro AS, Oslo, NO;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/800 ; C07K 1/400 ; C07K 5/08 ;
U.S. Cl.
CPC ...
A61K 3/800 ; C07K 1/400 ; C07K 5/08 ;
Abstract
The invention provides to the use of inhibitors of calcium-activated neutral proteases (CANPs) and their pharmaceutically acceptable addition salts or their active subunits in the field of tumor therapy, especially cancer therapy. The inhibitors can especially be used against protease-bound bound glycosaminoglycan substrate-dependent tumors and meiotic cell division. The inhibitors include heat-stable, tetrameric proteins of approximately 240 kD possessing active subunits, and tripeptides exhibiting inhibitory activity. The pharmaceutical compositions may be prepared in a manner known per se, with carriers or additives commonly used in the pharmaceutical industry.