The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2003
Filed:
Sep. 18, 2000
Applicant:
Inventors:
David John King, Bagshot, GB;
Alison Turner, Slough, GB;
Nigel Robert Arnold Beeley, Thame, GB;
Thomas Andrew Millican, Maidenhead, GB;
Assignee:
Celltech R&D Limited, Slough, GB;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/9395 ; A61K 3/940 ; A61K 3/942 ; C07K 1/600 ; C12P 2/108 ;
U.S. Cl.
CPC ...
A61K 3/9395 ; A61K 3/940 ; A61K 3/942 ; C07K 1/600 ; C12P 2/108 ;
Abstract
The invention provides a tri- or tetra-valent monospecific antigen-binding protein comprising three or four Fab fragments bound to each other covalently by a connecting structure, which protein is not a natural immunoglobuline. Further provided are novel connecting structures for use in assembling the proteins of the invention and means for attaching a labeling or effector group thereto. The proteins of the invention are useful, for example, in the treatment and diagnosis of cancer.