The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2003
Filed:
Jan. 13, 1994
Applicant:
Inventor:
Stephen K. Rhind, Buckinghamshire, GB;
Assignee:
Celltech Limited, Slough, GB;
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/600 ; G01N 3/3531 ;
U.S. Cl.
CPC ...
C07K 1/600 ; G01N 3/3531 ;
Abstract
Bis-maleimido cross-linking reagents join labelled antibodies having at least one sulphide interchain bridge. The conjugates have an enhanced binding capacity and have good blood clearance in vivo. The conjugates are of use in the diagnosis and therapy of tumors and may be prepared by reaction of the cross-linking reagent with the antibody.