The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2003
Filed:
May. 26, 2000
Applicant:
Inventors:
Andrew James Brown, Hitchin, GB;
Simon Jeremy Dowell, St. Albans, GB;
Assignee:
Glaxo Welcome Inc., Middlesex, GB;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 2/108 ; C12P 2/106 ; C12P 2/104 ; C12N 1/14 ; C07H 2/102 ;
U.S. Cl.
CPC ...
C12P 2/108 ; C12P 2/106 ; C12P 2/104 ; C12N 1/14 ; C07H 2/102 ;
Abstract
A chimeric G protein having yeast G (Gpa1p) amino acid sequences modified by a minimum of 3 amino acids positions within the C-terminal 10 amino acids by substitution by alternative amino acids, a transformed yeast cell comprising said chimeric G protein and a method of screening for a compound able to interact with a receptor comprising contacting a compound of interest with said yeast cell and observing the growth response of the cell or observing production of a reporter gene product.