The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 14, 2003
Filed:
Apr. 24, 2001
Applicant:
Inventors:
Khashayar Karimian, Mississauga, CA;
Tim Fat Tam, Woodbridge, CA;
Yong Tao, Brampton, CA;
Yiwei Li, Etobicoke, CA;
Gary Doucette, Downsview, CA;
Assignee:
Apotex Inc., Weston, CA;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 6/974 ; C07C 6/128 ;
U.S. Cl.
CPC ...
C07C 6/974 ; C07C 6/128 ;
Abstract
A process is disclosed for the preparation of simvastatin which enables highly regio selective C-methylation of the 2′-position group of lovastatin without requiring protection/deprotection of 13-OH of lovastatin and lactone ring opening/closure.