The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 14, 2003
Filed:
Aug. 23, 2001
Elfi Biedermann, Vaterstetten, DE;
Rolf Eisenburger, Kirchseeon, DE;
Max Hasmann, Neuried, DE;
Roland Löser, Feldafing, DE;
Benno Rattel, Munich, DE;
Friedemann Reiter, Putzbrunn, DE;
Barbara Schein, Neufahrn, DE;
Isabel Schemainda, Munich, DE;
Michael Schulz, Aschheim, DE;
Klaus Seibel, Gräfelfing-, DE;
Klaus Vogt, Munich, DE;
Katja Wosikowski, Poing, DE;
Klinge Pharma GmbH, Munich, DE;
Abstract
New biologically active compounds are described which inhibit the cellular formation of niacinamide mononucleotide, and essential intermediate of the NAD(P) biosynthesis in the cell. These compounds can represent the active ingredient of a pharmaceutical composition for the treatment of cancers, leukaemias or for immunosuppression. Furthermore, screening methods are described as a tool for detecting the above active compounds, and for examination of a given cell type for its dependency on niacinamide as a precursor for NAD synthesis.