The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 14, 2003

Filed:

Nov. 28, 2000
Applicant:
Inventors:

Jin Kyu Park, Seoul, KR;

Mork Soon Park, Taejeon, KR;

Dong Seon Kim, Taejeon, KR;

Il Ho Lim, Chungcheongbuk-do, KR;

Ung Kil Jee, Seoul, KR;

Pyung Keun Myung, Taejeon, KR;

San Beom Kim, Kunsan, KR;

Goo Young Jung, Chungcheongbuk-do, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/14 ; A61K 9/50 ; A01N 2/500 ;
U.S. Cl.
CPC ...
A61K 9/14 ; A61K 9/50 ; A01N 2/500 ;
Abstract

Disclosed is a method for preparing sustained release microparticles which release a physiologically active substance for long periods of time. The sustained release microparticles are prepared through a multi-emulsion process. A drug of interest is dissolved or dispersed in each of at least two oils to give at least two primary oil phases or emulsions. Each oil phase or emulsion contains a biodegradable polymer. The least two primary oil phases or emulsions are dispersed in one aqueous phase, synchronously or in succession. From the drug-dispersed solution, the organic solvents are removed to produce microparticles. Therefore, the drugs such as leutenizing hormone releasing hormones can be continuously released in vivo for prolonged periods of time, bringing about an improvement in the therapeutic effect.


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