The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6504035 B1

PDF
Full Text
Expired
Date of Patent:
Jan. 07, 2003

Filed:

Jan. 28, 2002
Applicant:
Inventors:

Amalija Narandja, Zagreb, HR;

Nevenka Lopotar, Zagreb, HR;

Marko Djerek, Zagreb, HR;

Dra{haeck over (z)}en Pavlović, Zagreb, HR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ;
U.S. Cl.
CPC ...
C07D / ; C07D / ;
Abstract

The present invention relates to derivatives of 3-deoxy desmycosin of the formula I, wherein, starting from triply protected desmycosin, there are performed an oxidation at C-3 in the first step and then, optionally, a hydrogenation of double bonds and an epoxidation followed by a reductive opening of the oxirane ring. The present invention also relates to derivatives of 3-deoxy-desmycosin of the formula II, wherein in the first step triacetyl desmycosin is hydrogenated and then, via an intermediate mesylate, it is converted to a 2,3-didehydro derivative; or 2,3-didehydro-desmycosin is subjected to epoxidation reactions followed by a reductive opening of the oxirane ring.


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Narandja, Amalija. (2003). 3-deoxy-desmycosin derivatives and process for their preparation (U.S. Patent No. 6504035). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6504035

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