The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 31, 2002
Filed:
Jul. 23, 2001
Applicant:
Inventors:
William Robert Carling, Bishops Stortford, GB;
Jose Luis Castro Pineiro, Bishops Stortford, GB;
Richard Thomas Lewis, Bishops Stortford, GB;
Kevin William Moore, Buntingford, GB;
Leslie Joseph Street, Little Hallingbury, GB;
Assignee:
Merck Sharp & Dohme Ltd., Hoddesdon, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/15025 ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/15025 ; C07D / ;
Abstract
1,2,4-triazolo[4,3-b]pyridazine derivatives, possessing a difluoro-or tri-fluoro-substituted phenyl ring at the 3-position, a triazolyl moiety at the 6-position, and a tert-butyl group at the 7-position, are selective ligands for GABA receptors, in particular having high affinity for the &agr;2 and/or &agr;3 subunit thereof, and are useful in the treatment of anxiety and convulsions.