The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 31, 2002

Filed:

Aug. 14, 2000
Applicant:
Inventors:

Kamal K. Midha, Hamilton, BM;

Mark Hirsh, Wellesley, MA (US);

Whe-Yong Lo, Canton, MA (US);

Assignee:

Peirce Management, LLC, Wellesley, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/20 ; A61K 9/48 ; A61K 9/14 ; A61K 9/52 ; A61K 9/22 ;
U.S. Cl.
CPC ...
A61K 9/20 ; A61K 9/48 ; A61K 9/14 ; A61K 9/52 ; A61K 9/22 ;
Abstract

Novel pharmaceutical dosage forms provide for pulsatile delivery of an antiarrhythmic agent that releases the drug in spaced apart “pulses.” The dosage forms are comprised of first, second and optional third dosage units, with each dosage unit having a different drug release profile. The dosage forms may comprise capsules housing compressed tablets or drug-containing beads, granules, or particles or may comprise a single tablet with the first, second and optional third dosage units incorporated therein, or a “coated core” dosage form. Methods of treatment using the pharmaceutical dosage forms are provided as well.


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