The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 24, 2002
Filed:
Mar. 03, 2000
Applicant:
Inventors:
Alexander Pletnev, Rockville, MD (US);
Ruhe Men, Rockville, MD (US);
Robert Chanock, Bethesda, MD (US);
Ching-Juh Lai, Bethesda, MD (US);
Assignee:
The United States of America as represented by the Department of Health & Human Services, Washington, DC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/912 ; A01N 6/300 ; C12N 1/500 ; C12P 2/106 ;
U.S. Cl.
CPC ...
A61K 3/912 ; A01N 6/300 ; C12N 1/500 ; C12P 2/106 ;
Abstract
A live, attenuated chimeric virus vaccine against tick-borne encephalitis virus comprising the preM and E structural genes of the tick-borne encephalitis Langat virus and the non-structural genes of the mosquito-borne dengue virus. The live chimeric vaccine was administered intraperitoneally and exhibited complete attenuation in mice while at the same time providing protection against subsequent challenge with the virulent parental Langat virus.