The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 24, 2002
Filed:
Oct. 22, 1999
Applicant:
Inventors:
Kathleen A. Stringer, Denver, CO (US);
Brooks M. Hybertson, Boulder, CO (US);
John E. Repine, Englewood, CO (US);
Joe M. McCord, Denver, CO (US);
Assignee:
University Technology Corporation, Boulder, CO (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/848 ; A61K 3/849 ; A61K 3/800 ;
U.S. Cl.
CPC ...
A61K 3/848 ; A61K 3/849 ; A61K 3/800 ;
Abstract
Plasminogen activator acts as an anti-inflammatory agent by inhibiting generation of superoxide anion by a mechanism that is not related to L-arginine, is not dependent on thrombolytic activity, and is not a function of oxygen free radical scavenging. Moreover, in in vivo models of inflammation, treatment with plasminogen activator reduces edema without inhibiting neutrophil infiltration in in vivo models of inflammation.