The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 17, 2002
Filed:
Feb. 28, 2001
Sarath P. Gunasekera, Vero Beach, FL (US);
Ross E. Longley, Vero Beach, FL (US);
Richard A. Isbrucker, Ontario, CA;
Gopal K. Paul, Ft. Pierce, FL (US);
Shirley A. Pomponi, Ft. Pierce, FL (US);
Amy E. Wright, Ft. Pierce, FL (US);
Harbor Branch Oceanographic Institution, Inc., Fort Pierce, FL (US);
Abstract
The subject invention provides novel compositions of biologically active discodermolide compounds which can advantageously be used for immunomodulation and/or treating cancer. The compounds of the subject invention have utility for use in the treatment of cancer, as tubulin polymerizers and as microtubule stabilization agents. The present invention also pertains to the identification of regions of the discodermolide molecule which are responsible for certain aspects of the bioactivity of discodermolide compounds.