The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 17, 2002

Filed:

Aug. 25, 2000
Applicant:
Inventors:

Thomas R. Tice, Birmingham, AL (US);

Jay K. Staas, Alabaster, AL (US);

Teresa M. Ferrell, Vestavia Hills, AL (US);

Peter Markland, Birmingham, AL (US);

Assignee:

Southern Research Institute, Birmingham, AL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 ; A61F 2/00 ;
U.S. Cl.
CPC ...
A61K 9/14 ; A61F 2/00 ;
Abstract

An injectable slow-release partial opioid agonist or opioid antagonist formulation is provided comprising a partial opioid agonist or opioid antagonist in a poly(D,L-lactide) excipient with a small amount of residual ethyl acetate. Upon intramuscular injection of the composition, a partial opioid agonist or opioid antagonist is released in a controlled manner over an extended period of time. The composition finds use in the treatment of heroin addicts and alcoholics to reduce consumption of the abused substances. Of particular interest are the drugs buprenorphine, methadone and naltrexone.


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