The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2002
Filed:
Apr. 09, 1999
Applicant:
Inventor:
Gregory R. Mundy, San Antonio, TX (US);
Assignee:
Osteoscreen, Inc., San Antonio, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/800 ; A61K 3/116 ;
U.S. Cl.
CPC ...
A61K 3/800 ; A61K 3/116 ;
Abstract
The present invention involves the identification and use of compositions for treating myeloma bone disease. The compositions inhibit proteasomal activity and decrease the activity of the transcription factor NF-&kgr;B. Assessment of a candidate compound for its ability to inhibit production or activity of proteasomal enzymes or NF-&kgr;B provides a useful means to identify agents to treat myeloma bone disease.