The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2002
Filed:
Sep. 21, 2000
Mary E. Brunkow, Seattle, WA (US);
David J. Galas, Mercer Island, WA (US);
Brian Kovacevich, Renton, WA (US);
John T. Mulligan, Seattle, WA (US);
Bryan W. Paeper, Seattle, WA (US);
Jeffrey Van Ness, Seattle, WA (US);
David G. Winkler, Seattle, WA (US);
Celltech R&D, Inc., Bothell, WA (US);
Abstract
Compositions and methods for increasing bone density using antibodies directed to a novel class or family human of TGF-&bgr; binding proteins are disclosed. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases associated with a loss of bone density, for example osteoporosis. The disclosed compositions include polypeptides, and their encoding polynucleotides, which specifically bind to at least one human bone morphogenic protein (BMP) selected from BMP-5 and BMP-6.