The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6489165 B1

PDF
Full Text
Expired
Date of Patent:
Dec. 03, 2002

Filed:

Jan. 16, 2001
Applicant:
Inventors:

Rajendra S. Bhatnagar, Burlingame, CA (US);

Steven B. Nicoll, San Francisco, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 ;
U.S. Cl.
CPC ...
C12N 5/00 ;
Abstract

Fibroblast cells are treated with a chemical inhibitor of protein kinase C such as staurosporine, in conjunction with functionally hypoxic micromass culture so as to be induced into chondrogenic differentiation. Such fibroblast-derived, chondrocyte-like cells may be seeded onto three-dimensional polymer scaffolds for use in the repair of articular cartilage lesions, and thus can obviate the need for invasive techniques to harvest autologous chondrocytes from a limited supply of existing articular cartilage, or to avoid the need for obtaining allogeneic chondrocytes from non-biocompatible donor tissues.


Find Patent Forward Citations

Bhatnagar, Rajendra. (2002). Chondrocyte-like cells useful for tissue engineering and methods (U.S. Patent No. 6489165). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6489165

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