The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2002
Filed:
Jan. 12, 2000
Applicant:
Inventors:
Richard Maurice Walmsley, Chorlton, GB;
Wolf Dietrich Heyer, Davis, CA (US);
Assignee:
Gentronix Limited, Manchester, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 ; C12Q 1/02 ; C12N 1/00 ; C12N 1/19 ; C12N 5/10 ; C12N 1/511 ; C12N 1/512 ; C12N 1/563 ; C12N 1/581 ;
U.S. Cl.
CPC ...
C12Q 1/68 ; C12Q 1/02 ; C12N 1/00 ; C12N 1/19 ; C12N 5/10 ; C12N 1/511 ; C12N 1/512 ; C12N 1/563 ; C12N 1/581 ;
Abstract
Recombinant DNA molecules comprising a regulatory element that activates gene expression in response to DNA damage operatively linked to a DNA sequence that encodes a light emitting reporter protein, recombinant vectors containing such DNA molecules and cells containing the DNA molecules or recombinant vectors. A method of detecting for the presence of an agent that causes or potentiates DNA damage is also disclosed which involves subjecting the above-described cells to a putative DNA damaging agent and monitoring the expression of the light emitting reporter protein from the cell.