The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 26, 2002
Filed:
Oct. 26, 1999
Pierre Chambon, Blaesheim, FR;
Thomas Lufkin, New York, NY (US);
David Lohnes, Montreal, CA;
Manuel Mark, Marschwiller, FR;
Andree Dierich, Strasbourg, FR;
Philippe Gorry, Pessac, FR;
Philippe Kastner, Strasbourg, FR;
Marianne Lemeur, Strasbourg, FR;
Cathy Mendelsohn, Englewood, NJ (US);
Other;
Abstract
The present invention provides mice which are deficient in the normal expression of one or more members of the RAR or RXR class of receptors, to mice heterozygous for such deficiency, and to cell lines, preferably pluripotent or totipotent cell lines, which are heterozygous or homozygous for such deficiency. The present invention further provides the use of any of the above mice and cell lines in situations where the absence of at least one RAR or RXR receptors, or the normal expression thereof, is desirable.