The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 26, 2002

Filed:

Jun. 02, 2000
Applicant:
Inventors:

Randall McCoy, McConnellsburg, PA (US);

Miles Augustus Libbey, III, Pennington, NJ (US);

Jle Liu, Scotch Plains, NJ (US);

Robert O. Williams, III, Austin, TX (US);

Assignee:

DelRx Pharmaceutical Corp., Jamesburg, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/12 ; A61K 9/10 ; A61K 3/810 ; A61K 3/812 ;
U.S. Cl.
CPC ...
A61K 9/12 ; A61K 9/10 ; A61K 3/810 ; A61K 3/812 ;
Abstract

A formulation for non-invasive delivery of pharmaceutical agents, particularly proteins and peptides, by absorption through a membrane at a targeted site is provided, along with a process of making the formulation. The formulation comprises a suspension of solid-phase dehydrated particles in a delivery medium. The particles comprise the dehydration product of the pharmaceutical agent and at least one of a surfactant and permeation enhancer, and the delivery medium preferably comprises a propellant for pressurized aerosol delivery of the formulation. The formulation can be conveniently delivered to the patient's targeted site where the pharmaceutical agent is absorbed through the mucosa to achieve a desired bioavailability.


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