The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2002
Filed:
Sep. 14, 1999
Applicant:
Inventors:
Assignee:
University of Pittsburgh of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 4/800 ; A61K 3/100 ; C12N 1/574 ; C12N 5/02 ; C12N 5/00 ;
U.S. Cl.
CPC ...
A61K 4/800 ; A61K 3/100 ; C12N 1/574 ; C12N 5/02 ; C12N 5/00 ;
Abstract
The use of professional antigen presenting cells genetically modified to enhance expression of an immunostimulatory cytokine is disclosed for the treatment of individuals having tumors or infections. The genetically modified professional antigen presenting cells are injected directly at or near the site of the tumor or infection. Preferred professional antigen presenting cells include dendritic cells, and preferred immunostimulatory cytokines include interleukins such as IL-12.