The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 12, 2002

Filed:

Jun. 16, 2000
Applicant:
Inventors:

Donald E. Macfarlane, Iowa City, IA (US);

Lucjan Strekowski, Stone Mountain, GA (US);

Lori Manzel, Cedar Rapids, IA (US);

Fyaz M. D. Ismail, Stockton on Tees, GB;

Gordon B. Barlin, Turner, AU;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/144 ; A61K 3/147 ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/144 ; A61K 3/147 ; C07D / ; C07D / ;
Abstract

The present invention relates generally to the field of immunology. More particularly it concerns compositions and methods for inhibiting stimulation of the immune system. The compounds and methods comprise compounds that are analogs and derivatives of chloroquine, such as 4-aminoquinolines, and other weak bases. They can be used in preventative and therapeutic treatments of autoimmune diseases and phenomena, transplant rejection such as host-versus-graft disease, and sepsis.


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