The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 12, 2002
Filed:
Sep. 26, 2000
Applicant:
Inventors:
Heinrich Göttlinger, Brookline, MA (US);
Heide Reil, Braunschweig, DE;
Anatoly Bukovsky, Bellevue, WA (US);
Assignee:
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/5867 ; C12N 1/563 ; C12N 1/564 ;
U.S. Cl.
CPC ...
C12N 1/5867 ; C12N 1/563 ; C12N 1/564 ;
Abstract
Vector systems that encode viral proteins that will assemble into an infectious lentivirus particle having a deletion of the lentiviral matrix are described. In one embodiment the vectors encode a lentiviral envelope protein that contains a deletion of the cytoplasmic tail. In a second embodiment a heterologous envelope as compared to the lentivirus is used such as an envelope protein that targets an endocytic compartment.