The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 12, 2002
Filed:
Dec. 17, 1998
Makoto Saruhashi, Kanagawa-ken, JP;
Masatomi Sasaki, Kanagawa-ken, JP;
Asahi Medical Co., Ltd., Tokyo, JP;
Abstract
A manufacturing method of an artificial organ formed of a material having a solubility parameter &dgr; of not more than 13 (cal/cm ) involves filling micropores of the body fluid treatment membrane with a filling solution having no or little solubility with respect to a fat-soluble modifier solution, and coating a portion of the body fluid treatment membrane with the fat-soluble modifier by contacting the fat-soluble modifier solution. With this method substantially only the necessary portions need to be coated with the fat-soluble modifier so that a smaller amount of the fat-soluble modifier may be employed. A microporous membrane is formed of a synthetic polymer substrate having a solubility parameter &dgr; of not more than 13 (cal/cm ) , with not less than 50 wt % of fat-soluble modifier included in the hollow fiber membrane being held on a surface which may contact body fluid. The membrane possesses the following sieve coefficients measured by dextrans: no more than 0.4 when a dextran with a molecular weight of 100,000 is employed; and not less than 0.5 when another dextran with a molecular weight of 10,000 is employed.