The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 05, 2002
Filed:
Jun. 30, 1999
Applicant:
Inventors:
Gennaro Ciliberto, Rome, IT;
Isabella Saggio, Rome, IT;
Rocco Savino, Pomerzia RM, IT;
Michel Perricaudet, Ecrosnes, FR;
Assignee:
Other;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 2/106 ; C12P 2/102 ; C12P 2/104 ; C12N 1/506 ; C12N 1/500 ;
U.S. Cl.
CPC ...
C12P 2/106 ; C12P 2/102 ; C12P 2/104 ; C12N 1/506 ; C12N 1/500 ;
Abstract
The subject matter of the present invention are recombinant defective adenoviruses comprising a heterologous DNA sequence coding for a mutein having the activity of human Interleukin 6 (hIL-6) antagonists or superantagonist. Moreover, the invention refers to therapeutical uses thereof, in particular for preparing pharmaceutical compositions for treating and/or preventing pathologies caused by hIL-6 overproduction.