The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 05, 2002
Filed:
Jun. 22, 1999
Applicant:
Inventors:
David Bermudes, Wallingford, CT (US);
Kenneth Brooks Low, Guilford, CT (US);
Assignee:
Vion Pharmaceuticals, Inc., New Haven, CT (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/9112 ; C07H 2/104 ; C07K 1/4255 ; C12N 1/20 ;
U.S. Cl.
CPC ...
A61K 3/9112 ; C07H 2/104 ; C07K 1/4255 ; C12N 1/20 ;
Abstract
The invention is directed to mutant having a genetically modified msbB gene in which the mutant Salmonella is capable of targeting solid tumors. The invention further relates to the therapeutic use of the mutant Salmonella for growth inhibition and/or reduction in volume of solid tumors.