The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2002
Filed:
Feb. 16, 2001
Applicant:
Inventors:
Paul R. Carlier, Blacksburg, VA (US);
Yifan Han, Kowloon, HK;
Yuan-Ping Pang, Rochester, MN (US);
Da-Ming Du, Beijing, CN;
Assignee:
The Hong Kong University of Science and Technology, Kowloon, HK;
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/147 ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/147 ; C07D / ; C07D / ;
Abstract
The invention relates to dimeric compounds comprising two 5-amino-5,6,7,8-tetrahydroquinoline fragments joined together by a divalent linking group, processes for their preparation, intermediates for their preparation, pharmaceutical compositions containing such dimeric compounds and the use of such compounds as cholinesterase inhibitors and in the treatment of neurodegenerative diseases, such as Alzheimer's Disease and myasthenia gravis.