The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2002
Filed:
May. 05, 1998
Applicant:
Inventors:
Orest W. Blaschuk, Westmount, CA;
James Matthew Symonds, Ottawa, CA;
Barbara J. Gour, Kemptville, CA;
Assignee:
Adherex Technologies, Inc., Ottawa, CA;
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/808 ; A61K 3/812 ; A61K 3/816 ;
U.S. Cl.
CPC ...
A61K 3/808 ; A61K 3/812 ; A61K 3/816 ;
Abstract
Modulating agents for inhibiting or enhancing OB-cadherin mediated cell adhesion are provided. The modulating agents comprise one or more of: (a) an OB-cadherin CAR sequence; (b) a peptide analogue or peptidomimetic thereof; (c) an antibody or antigen-binding fragment thereof that specifically binds an OB-cadherin CAR sequence; and/or (d) a polynucleotide encoding any of the foregoing peptide sequences. Methods for using such modulating agents for modulating OB-cadherin-mediated cell adhesion in a variety of contexts are also provided.