The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2002
Filed:
Oct. 17, 1997
Elliott Richelson, Ponte Vedra Beach, FL (US);
Beth Marie Tyler, Neptune Beach, FL (US);
Daniel J. McCormick, Rochester, MN (US);
Bernadette Marie Cusack, Jacksonville Beach, FL (US);
Clark V. Hoshall, Ponte Vedra Beach, FL (US);
Christopher Lee Douglas, Jacksonville, FL (US);
Karen Jansen, Jacksonville, FL (US);
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
Abstract
The invention involves methods and materials for extracellularly administering PNA oligomers to living cells. Specifically, the invention provides methods of treating living cells with PNA oligomers such that the oligomers cross biological barriers and engender a biological response in a sequence specific manner. This invention also provides methods of screening potential PNA oligomers for the ability to engender a sequence specific biological response. Further, this invention provides methods of identifying the function of polypeptides and of determining the relative turnover rate of functional polypeptides.