The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2002
Filed:
Jul. 24, 2000
Applicant:
Inventors:
Mathieu Hubertus Maria Noteborn, Leiderdorp, NL;
Astrid Adriana Anna Maria Danen-Van Oorschot, Berkel en Rodenrijs, NL;
Assignee:
Leadd B.V., Leiden, NL;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/00 ; C12Q 1/68 ; C12P 2/106 ; C12N 1/563 ;
U.S. Cl.
CPC ...
C12Q 1/00 ; C12Q 1/68 ; C12P 2/106 ; C12N 1/563 ;
Abstract
The invention relates to activation of apoptosis by means of interference of the function of Bip-like compounds. Also the invention relates to anti-tumor therapies with compounds, which negatively interfere with Bip-like compounds leading to induction of apoptosis, resulting in the elimination of tumor cells. Also the invention relates to therapies for diseases related to aberrant apoptosis induction, such as auto-immune diseases. Also the invention describes the diagnosis of cells, which are susceptible to apoptin or apoptin-like induced apoptosis.