The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 2002
Filed:
Jun. 01, 2001
Applicant:
Inventors:
Thomas Charles Boone, Newbury Park, CA (US);
Ellen Ngoi Yin Cheung, Agoura, CA (US);
Susan Irene Hershenson, Newbury Park, CA (US);
John David Young, Thousand Oaks, CA (US);
Assignee:
Amgen Inc., Thousand Oaks, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/800 ; A01N 3/718 ; C07K 1/00 ;
U.S. Cl.
CPC ...
A61K 3/800 ; A01N 3/718 ; C07K 1/00 ;
Abstract
The in vivo circulating life and/or absorption of Neurophic Factor-3 (NT-3) is increased by generating certain substitution analogs of the native protein sequence that result in a lower isoelectric point and charge in relation to NT-3 of native sequence.