The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 15, 2002
Filed:
Nov. 01, 2000
Applicant:
Inventors:
Dearg S Brown, Macclesfield, GB;
George R Brown, Macclesfield, GB;
Assignee:
AstraZeneca AB, Sodertalje, SE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C / ; A61K 3/1165 ; A61P 2/900 ; A61P 3/702 ;
U.S. Cl.
CPC ...
C07C / ; A61K 3/1165 ; A61P 2/900 ; A61P 3/702 ;
Abstract
The invention concerns amide derivatives of Formula (I) wherein: R and R include hydroxy, C alkoxy, mercapto, C akylthio, amino and heterocyclyl; m and p are independently 0-3; R is halo, cyano or C alkoxy; q is 0-4; and R is aryl or cycloalkyl wherein R is optionally substituted with up to 3 substituents having any value defined for each R group; or a pharmaceutically-acceptable salt or in-vivo-cleavable ester thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by cytokines.