The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 15, 2002
Filed:
Jul. 06, 2001
Applicant:
Inventor:
Rick A. Rogers, Needham, MA (US);
Assignee:
Rogers Imaging Corp., Needham, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N 1/30 ; G01N 3/353 ; C12Q 1/00 ;
U.S. Cl.
CPC ...
G01N 1/30 ; G01N 3/353 ; C12Q 1/00 ;
Abstract
The present invention clarifies and contrasts stain intact biological tissue samples for microscopic analysis. A biological specimen is depigmented and then contacted with a fluorescent dye, wherein the dye stains the specimen nonspecifically. The depigmented, non-specifically stained specimen is equilibrated in a clearing solution, wherein the refractive index of the clearing solution approximates that of the specimen, thereby preparing the biological specimen for visual analysis.