The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 15, 2002
Filed:
May. 08, 2000
Applicant:
Inventors:
Gunnar Nilsson, Vattholma, SE;
Zou Xiang, Uppsala, SE;
Assignee:
Innoventus Project AB, Uppsala, SE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 ; C07H 2/104 ;
U.S. Cl.
CPC ...
C12Q 1/68 ; C07H 2/104 ;
Abstract
A method of treatment of mast cell mediated inflammatory disorders in mammals comprising regulating the longevity and activity of activated mast cells by inhibiting the expression and/or function of the anti-apoptotic A-1/bfl-1 gene or gene product. The invention also provides the development and use of a compound capable of inhibiting the expression and/or function of the anti-apoptotic A-1/bfl-1 gene or gene product for the manufacture of a medicament for treating mast cell mediated inflammation in human tissues by regulating the longevity and activity of activated mast cells.