The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 08, 2002
Filed:
Apr. 05, 2000
Mikael Kubista, Mölnlycke, SE;
Nicke Svanvik, Göteborg, SE;
Gunnar Westman, Härryda, SE;
Lightup Technologies AB, Huddinge, SE;
Abstract
The invention relates to a method for preparing a probe, thus prepared probe, and the use of such a probe for selectively choosing sequence for nucleic acid diagnostic purposes, using preferably homogenous solutions. The invention is based upon a great number of probes having different sequences and lengths which all are complementary to different parts of the nucleic acid to be detected, which probes are synthetised on a solid matrix. The signal which they provide in non-hybridized condition is monitored, whereupon the nucleic acid to be detected is added, and the signal is monitored again. Those probes that show the most significant difference in signal are those, from a sensitivity point of view, that are the most suitable one.