The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 08, 2002
Filed:
Aug. 07, 2000
Applicant:
Inventors:
Motowo Nakajima, Hyogo, JP;
Minako Funakubo, Kanagawa, JP;
Assignee:
Novartis AG, Basel, CH;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 2/106 ; C12N 9/00 ; C12N 9/24 ; C12N 9/42 ; C12N 1/20 ;
U.S. Cl.
CPC ...
C12P 2/106 ; C12N 9/00 ; C12N 9/24 ; C12N 9/42 ; C12N 1/20 ;
Abstract
This invention relates to identified polynucleotides, polypeptides encoded by such polynucleotides, the use of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides. More particularly, a polypeptide of the present invention is “heparanase”obtainable from the human SV40-transformed fibroblast cell line ATCC CCL 75.1. The heparanase is an endoglucuronidase capable of specifically degrading heparan sulfate into 6 to 20 kDa fragments.