The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 08, 2002
Filed:
Aug. 31, 1999
Methods of screening compounds for their ability to inhibit the production of inflammatory cytokines
Applicant:
Inventors:
Christopher A. Gabel, Ledyard, CT (US);
Richard J. Griffiths, East Lyme, CT (US);
James F. Eggler, Stonington, CT (US);
Mark A. Dombroski, Waterford, CT (US);
Kieran Geoghegan, Mystic, CT (US);
Assignee:
Pfizer Inc., New York, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 3/353 ; G01N 3/3567 ; C07K 1/00 ; C07H 2/104 ; C07C / ;
U.S. Cl.
CPC ...
G01N 3/353 ; G01N 3/3567 ; C07K 1/00 ; C07H 2/104 ; C07C / ;
Abstract
The present invention relates to the identification of diarylsulfonylurea binding proteins (DBPs) as therapeutic targets for agents that suppress the release of inflammatory mediators such as interleukin IL-1 and IL-1&bgr;.