The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 08, 2002
Filed:
May. 20, 1999
Applicant:
Inventors:
Paul F. Agris, Raleigh, NC (US);
Salman Ashraf, Raleigh, NC (US);
Assignee:
North Carolina State University, Raleigh, NC (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 ; C12N 1/21 ; C07H 2/104 ;
U.S. Cl.
CPC ...
C12Q 1/68 ; C12N 1/21 ; C07H 2/104 ;
Abstract
Methods of inhibiting microbial propagation, and screening for compounds that inhibit microbial propagation, are described. A method of inhibiting microbial propagation comprises inhibiting ribosomal binding of a specific microbial tRNA in the microbe by an amount sufficient to inhibit microbe propagation. A method of screening for compounds useful for inhibiting microbial propagation comprises contacting a specific microbial tRNA to a ribosome that binds that tRNA in the presence of the test compound, and then determining whether the compound inhibits the binding of that tRNA.