The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2002

Filed:

Feb. 27, 2001
Applicant:
Inventors:

Michael David Bentley, Huntsville, AL (US);

Xuan Zhao, Huntsville, AL (US);

Jeremy Lloyd Clark, Harvest, AL (US);

Assignee:

Shearwater Corporation, Huntsville, AL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/180 ; A61K 3/174 ; A61K 3/1335 ; A61K 3/35 ; A61K 3/134 ;
U.S. Cl.
CPC ...
A61K 3/180 ; A61K 3/174 ; A61K 3/1335 ; A61K 3/35 ; A61K 3/134 ;
Abstract

The present invention provides water-soluble polymer conjugates of the anti-malarial drug, artelinic acid, using water soluble and non-peptidic polymer backbones, such as poly(ethylene glycol). The invention includes conjugates made using mPEG, bifunctional PEG and multi-arm PEG. The invention further includes a method of forming such conjugates and a method of treating malaria using the conjugates.


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