The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 01, 2002

Filed:

Sep. 14, 2000
Applicant:
Inventors:

Motokazu Iwata, Takatsuki, JP;

Teruaki Kuriyama, Higashiosaka, JP;

Megumi Fujita, Otsu, JP;

Keiichi Fujiwara, Kyoto, JP;

Shiro Kato, Sakai, JP;

Hiroshi Harada, Suita, JP;

Akihito Fujii, Ikoma, JP;

Osamu Odai, Hirakata, JP;

Hitoshi Kawashima, Osaka, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/140 ; C07D / ; A61P 4/300 ;
U.S. Cl.
CPC ...
A61K 3/140 ; C07D / ; A61P 4/300 ;
Abstract

The present invention provides a solid preparation comprising a crystal of [3-[(2R)-[[(2R)-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1H-indol-7-yloxy]acetic acid (Compound A), especially a crystal of Compound A having a particle size of not larger than 100 &mgr;m at the cumulative weight distribution value of 50%, and not larger than 200 &mgr;m at the cumulative weight distribution value of 95%, preferably a solid preparation having the excellent stability and the content uniformity of Compound A, which is prepared by preparing granules of the crystal of Compound A with fillers, disintegrants and binders, and then followed by mixing said granules with external excipients.


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