The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 2002
Filed:
Jul. 02, 1999
Applicant:
Inventors:
Paul F. Jackson, Bel Air, MD (US);
Keith M. Maclin, Baltimore, MD (US);
Eric Wang, Baltimore, MD (US);
Barbara S. Slusher, Kingsville, MD (US);
Rena S. Lapidus, Baltimore, MD (US);
Pavel Majer, Sykesville, MD (US);
Assignee:
Guilford Pharmaceutical Inc., Baltimore, MD (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/166 ; A61K 3/1435 ; A61K 3/119 ;
U.S. Cl.
CPC ...
A61K 3/166 ; A61K 3/1435 ; A61K 3/119 ;
Abstract
The present invention relates to N-Acetylated &agr;-Linked Acidic Dipeptidase (NAALADase) inhibitors enzyme activity, pharmaceutical compositions comprising such inhibitors, and methods of their use to inhibit NAALADase enzyme activity, thereby effecting neuronal activities, inhibiting angiogenesis, and treating glutamate abnormalities, compulsive disorders, prostate diseases, pain and diabetic neuropathy.