The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 2002
Filed:
Apr. 27, 1999
Applicant:
Inventors:
Patrick J. Concannon, Bainbridge Island, WA (US);
Christine S. Vissinga, Seattle, WA (US);
Karen M. Cerosaletti, Seattle, WA (US);
Raymonda Varon-Mateeva, Berlin, DE;
Karl Sperling, Berlin, DE;
André Wiesmann da Silva Reis, Berlin, DE;
Assignee:
Virginia Mason Research Center, Seattle, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 ; C07H 2/102 ;
U.S. Cl.
CPC ...
C12Q 1/68 ; C07H 2/102 ;
Abstract
The present invention relates to a novel gene, NBS1, and its gene product, nibrin. In addition, it relates to methods for detecting mutations or polymorphisms of the gene that are associated with Nijmegen breakage syndrome in patients. Such mutations may be used to diagnose a predisposition to the development of certain pathological conditions in these patients.