The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 2002
Filed:
May. 04, 1999
Jan Adrianus Verschoor, Pretoria, ZA;
Sandra Noel Bye, Hilton, ZA;
Abstract
The invention relates to a diagnostic test for the detection and identification of Mycobacterium species in biological specimens of human and animal origin. The test is based on the immunological detection of one or more antigens originating from Mycobacterium. To enable the detection of an antibody-antigen reaction, the antibodies specific for these antigens can be labelled with an enzyme or fluorescent dye or attached to latex particles or any other suitable label. The diagnostic test may be in a form of ELISA and may or may not require concentration of the Mycobacterium antigens prior to the actual test. The invention comprises: the selection and procurement of a suitable mycobacterial species and strain, the isolation and purification of the antigens, preparation of the necessary conjugates for the immunization of the experimental animals using various carrier molecules, the development of an assay for monitoring the antibody production, caracterization of the antibodies specific for the Mycobacterium antigen/antigens and the development of a diagnostic assay/kit.