The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 2002
Filed:
Sep. 03, 1998
Applicant:
Inventors:
Michael T. White, La Jolla, CA (US);
John S. O'Brien, La Jolla, CA (US);
David E. Wright, Ramona, CA (US);
Assignee:
Myelos Corporation, San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/900 ; A61K 3/800 ; A61K 3/816 ; A01N 3/718 ; C07K 1/400 ;
U.S. Cl.
CPC ...
A61K 3/900 ; A61K 3/800 ; A61K 3/816 ; A01N 3/718 ; C07K 1/400 ;
Abstract
Retro-inverso peptide analogs derived from the active neurotrophic region of saposin C. The saposin C-derived peptides (prosaptides) induce neurite outgrowth in vitro, prevent programmed cell death, induce myelination and have an analgesic effect. They are useful in the treatment of central and peripheral nervous system disorders and pain management. The retro-inverso peptides are significantly more resistant to metabolic degradation than the corresponding non-inverted peptides.