The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2002
Filed:
Aug. 04, 2000
Applicant:
Inventors:
Sarita Chauhan, Landenburg, PA (US);
Robert Dicosimo, Rockland, DE (US);
Robert D. Fallon, Elkton, MD (US);
John E. Gavagan, Wilmington, DE (US);
Mark S. Payne, Wilmington, DE (US);
Assignee:
E. I. du Pont de Nemours & Company, Wilmington, DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 5/108 ; C07C 6/976 ;
U.S. Cl.
CPC ...
C07C 5/108 ; C07C 6/976 ;
Abstract
This invention relates to a process for preparing dicarboxylic acid monoesters from cyanocarboxylic acid esters. More particularly, using the nitrilase from 72W (ATCC 55745) in various forms as an enzyme catalyst, an aliphatic or aromatic cyanocarboxylic acid ester is converted to the corresponding dicarboxylic acid monoester with high chemoselectivity at 100% conversion. An embodiment of the invention also provides a process for obtaining high chemoselectively and high regioselectivity.