The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 24, 2002

Filed:

Jun. 04, 1997
Applicant:
Inventors:

Tadeusz J. Kochel, Frederick, MD (US);

Kevin R. Porter, Gaithersburg, MD (US);

Kanakatte Raviprakash, Silver Spring, MD (US);

Stephen L. Hoffman, Gaithersburg, MD (US);

Curtis G. Hayes, Frederick, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/1711 ; A61K 3/912 ;
U.S. Cl.
CPC ...
A61K 3/1711 ; A61K 3/912 ;
Abstract

A vaccine for promoting an immune response in a mammalian subject includes a eucaryotic plasmid expression vector which include at least part of the envelope gene and optionally, the PreM gene of dengue virus. In order to minimize immune enhancement, vaccines of up to the four serotypes of dengue are combined in a single vaccine. The vaccine in a suitable pharmaceutical carrier constitutes a pharmaceutical composition which is injected into the subject.


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