The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 17, 2002
Filed:
Sep. 08, 1995
Hyun S. Lillehoj, West Friendship, MD (US);
B. Nichols Majorie, Columbia, MD (US);
The United States of America as represented by the Secretary of Agriculture, Washington, DC (US);
Abstract
A stable chicken hybridoma secreting a monoclonal antibody (mAb) that detects the conoid structure of ( ) sporozoites has been developed. The hybridoma is made by fusing a thymidine kinase (TK)-deficient chicken myeloma with spleen cells from chickens immunized with sporozoite antigen. The monoclonal antibody recognizes sporozoite proteins on the conoid of the anterior tip of sporozoites. The monoclonal antibody has been shown to inhibit the invasion of sporozoites into CD8 T cells in vitro thereby indicating its role in the recognition of host cells during the invasion process following infection with Eimeria parasites.